Very little data exists on the pharmacology, metabolism, and toxicity of 4-aco-dmt. ![]() 4-aco-dmt’s classical psychedelic effects and favorable tolerability profile has led it to become popular among novel psychoactive substance users who seek mystical or entheogenic experiences. characteristic effects include geometric visual hallucinations, time distortion, enhanced introspection, euphoria, and ego loss. like psilocybin, 4-aco-dmt is theorized to act as a prodrug to psilocin, which may account for this similarity. Subjective effects are reported to be nearly identical to those of psilocybin mushrooms. reports of recreational use began to surface following its appearance on the online research chemical market in the 2010s. nichols suggested it as a useful alternative to psilocybin for pharmacological research. however, its pharmacology and subjective effects were not explored. The synthesis of 4-aco-dmt was first reported in 1963 by albert hofmann and franz troxler. it belongs to a group known as the substituted tryptamines which act by stimulating serotonin receptors in the brain. ![]() 4-aco-dmt is chemically similar to psilocybin, the active ingredient in psilocybin mushrooms ( magic mushrooms). ![]() 4-AcO-DMT, 4-Acetoxy-DMT, Psilacetin, O-Acetylpsilocin, “Synthetic mushrooms”ģ-1H-indol-4-yl acetateĤ-acetoxy-n,n-dimethyltryptamine (also known as 4-aco-dmt, 4-acetoxy-dmt, o-acetylpsilocin, and psilacetin) is a novel psychedelic substance of the tryptamine class.
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